Topic: Bridging the gap: Examples of translational nephrology and team medicine
Acht Teilprojektleiter*innen aus der Nephrologie
(2021) SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. J Am Soc Nephrol, doi: 10.1681/ASN.2020081126. [Epub ahead of print]
(2021) Hypertensive Erkrankungen in der Schwangerschaft [Hypertensive Disorders in Pregnancy] Dtsch Med Wochenschr, doi: 10.1055/a-1233-7685. [Article in German]
(2021) Single-cell mRNA profiling reveals changes in solute carrier expression and suggests a metabolic switch during zebrafish pronephros development Am J Physiol Renal Physiol, doi: 10.1152/ajprenal.00610.2020.
(2021) Therapy with lopinavir/ritonavir and hydroxychloroquine is associated with acute kidney injury in COVID-19 patients PLoS One, doi: 10.1371/journal.pone.0249760.
(2021) A Novel Model for Nephrotic Syndrome Reveals Associated Dysbiosis of the Gut Microbiome and Extramedullary Hematopoiesis. Cells, doi: 10.3390/cells10061509.
(2021) Ruptured Intrarenal Arterial Aneurysm in a Patient With Granulomatosis With Polyangiitis J Rheumatol, doi: 10.3899/jrheum.190986.
(2021) Risk Factors and Management of Leukopenia After Kidney Transplantation: A Single-Center Experience Transplant Proc, doi: 10.1016/j.transproceed.2021.04.011.
(2020) Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules Sci Rep, doi: 10.1038/s41598-020-72905-8.
(2020) A Localized Scaffold for cGMP Increase Is Required for Apical Dendrite Development Cell Rep, DOI: 10.1016/j.celrep.2020.03.083
(2020) Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans Nat Genet, doi: 10.1038/s41588-019-0567-8
(2020) Divergent function of polycystin 1 and polycystin 2 in cell size regulation Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2019.10.074.
(2020) The acetyltransferase p300 regulates NRF2 stability and localization Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2020.02.006.
(2020) A molecular mechanism explaining albuminuria in kidney disease Nat Metab, doi: 10.1038/s42255-020-0204-y.
(2020) Clinical decision making in small non-functioning VHL-related incidentalomas Endocr Connect, doi: 10.1530/EC-20-0208.
(2020) Subcutaneous Enoxaparin Safely Facilitates Bedside Sustained Low-Efficiency Hemodialysis in Hypercoagulopathic Coronavirus Disease 2019 Patients-A Proof-of-Principle Trial Crit Care Explor, doi: 10.1097/CCE.0000000000000155.
(2020) Long-term Follow-up of ABO-Incompatible Kidney Transplantation in Freiburg, Germany: A Single-Center Outcome Report Transplant Proc, doi: 10.1016/j.transproceed.2020.09.001.
(2020) Comparison of different anticoagulation strategies for renal replacement therapy in critically ill patients with COVID-19: a cohort study. BMC Nephrol, doi: 10.1186/s12882-020-02150-8.
(2019) Primary decidual zone formation requires Scribble for pregnancy success in mice Nat Commun, doi: 10.1038/s41467-019-13489-4.
(2019) TBC1D8B Mutations Implicate RAB11-Dependent Vesicular Trafficking in the Pathogenesis of Nephrotic Syndrome J Am Soc Nephrol, doi: 10.1681/ASN.2019040414.
(2019) Growth characteristics and therapeutic decision markers in von Hippel-Lindau disease patients with renal cell carcinoma Orphanet J Rare Dis, doi: 10.1186/s13023-019-1206-2.
(2019) Impact of Diabetic Stress Conditions on Renal Cell Metabolome Cells, doi: 10.3390/cells8101141.
(2019) CBP-1/p300 acetyltransferase regulates SKN-1/Nrf cellular levels, nuclear localization, and activity in C. elegans Exp Gerontol, doi: 10.1016/j.exger.2019.110690.
(2019) Metabolic perturbations caused by depletion of nephronophthisis factor Anks6 in mIMCD3 cells Metabolomics, doi: 10.1007/s11306-019-1535-0.
(2019) Kidney embolization induces prompt organ response in a 86-year-old patient with MGRS-related AL-amyloidosis Hemodial Int, doi: 10.1111/hdi.12707.
(2019) GFR estimation in lenalidomide treatment of multiple myeloma patients: a prospective cohort study. Clin Exp Nephrol, doi: 10.1007/s10157-018-1626-7.
(2018) Kidney embolization induces prompt organ response in a 86-year-old patient with MGRS-related AL-amyloidosis Hemodial Int, E59-E64
(2018) CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury Nat Commun, 3660
(2018) GFR estimation in lenalidomide treatment of multiple myeloma patients: a prospective cohort study Clin Exp Nephrol, 199-206
(2018) Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells J Cancer Res Clin Oncol, 1933-1944
(2018) The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism PLoS Biol, e2005651
(2018) Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney EMBO J, doi: 10.15252/embj.201798615
(2018) Metabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate Sci Rep, doi: 10.1038/s41598-018-27389-y.
(2018) CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans Oncotarget, doi: 10.18632/oncotarget.24039.
(2018) Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs) Sci Rep, doi: 10.1038/s41598-018-22073-7.
(2018) A model to predict disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD): the ADPKD Outcomes Model BMC Nephrol, doi: 10.1186/s12882-017-0804-2.
(2018) Treating C3 glomerulopathy with eculizumab BMC Nephrol, doi: 10.1186/s12882-017-0802-4.
(2017) EpCAM controls morphogenetic programs during zebrafish pronephros development Biochem Biophys Res Commun, 209-215
(2017) Role of primary cilia in non-dividing and post-mitotic cells Cell Tissue Res, 11-25
(2017) Targeting mTOR Signaling Can Prevent the Progression of FSGS J Am Soc Nephrol, 2144-2157
(2017) Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. Nephrol Dial Transplant, 325-332
(2016) Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors Nat Cell Biol, 1269-1280
(2016) Cell cycle controls stress response and longevity in C. elegans Aging (Albany NY), 2100-2126
(2016) Successful Management of Calciphylaxis in a Kidney Transplant Patient: Case Report Transplant Direct, e70
(2016) A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes JCI Insight, doi: 10.1172/jci.insight.86177
(2016) ANKS3 is mutated in a family with autosomal recessive laterality defect Hum Genet, 1233-1239
(2016) Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies Nephrol Dial Transplant, 325-332
(2016) mTORC2 critically regulates renal potassium handling J Clin Invest, 1773-82
(2016) FAT1 mutations cause a glomerulotubular nephropathy Nat Commun, 10822
(2016) One hundred ABO-incompatible kidney transplantations between 2004 and 2014: a single-centre experience Nephrol Dial Transplant, 663-71
(2016) The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product Eur J Hum Genet, 774-8
(2016) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease Nephrol Dial Transplant, 284-9
(2015) TSC1 Activates TGF-beta-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition Dev Cell 32, 617-30
(2015) Anks3 interacts with nephronophthisis proteins and is required for normal renal development Kidney Int, doi: 10.1038/ki.2015.17
(2015) The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin Development 142, 174-84
(2015) The Future of Polycystic Kidney Disease Research-As Seen By the 12 Kaplan Awardees J Am Soc Nephrol, Ahead of print
(2015) Autosomal dominant polycystic kidney disease: the changing face of clinical management Lancet 385, 1993-2002
(2015) SUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7 PloS One, doi: 10.1371/journal.pone.0130275
(2015) Heart failure in a cohort of patients with chronic kidney disease: the GCKD study PLoS One, doi: 10.1371/journal.pone.0122552
(2015) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease Nephrol Dial Transplant, ahead of print
(2015) The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells J Cell Biol, doi: 10.1083/jcb.201502043.
(2014) Effect of everolimus on polycystic liver volume in autosomal dominant polycystic kidney disease Clin Exp Nephrol, ahead of print
(2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress Proc Natl Acad Sci U S A, 111, E2817-26
(2014) Hantavirus infection with severe proteinuria and podocyte foot-process effacement Am J Kidney Dis 64, 452-456
(2014) Calciphylaxis Lancet 383, 1067.
(2014) Interaction with the Bardet-Biedl Gene Product TRIM32/BBS11 Modifies the Half-life and Localization of Glis2/NPHP7 J Biol Chem 289, 8390-401.
(2014) Unraveling the Role of Podocyte Turnover in Glomerular Aging and Injury J Am Soc Nephrol., 4, 707-716
(2013) A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish PLoS One 8, e72549.
(2013) The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly Nephrol Dial Transplant 28, 2744-53.
(2013) TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development Dev Biol 384, 214-27.
(2013) ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3 Nat Genet 45, 951-6.
(2013) Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells PLoS One 8, e62165.
(2013) Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis J Am Soc Nephrol 24, 727-43.
(2013) N-wasp is required for stabilization of podocyte foot processes J Am Soc Nephrol 24, 713-21.
(2013) aPKClambda/iota and aPKCzeta contribute to podocyte differentiation and glomerular maturation J Am Soc Nephrol 24, 253-67.
(2012) Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury Autophagy 8, 826-37.
(2012) Role of the polarity protein Scribble for podocyte differentiation and maintenance PLoS One 7, e36705.
(2012) YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation PLoS One 7, e35735.
(2012) Inversin, Wnt signaling and primary cilia Differentiation 83, S49-55.
(2012) The German Chronic Kidney Disease (GCKD) study: design and methods Nephrol Dial Transplant 27, 1454-60.
(2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice J Clin Invest 121, 2197-209.
(2011) Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish Hum Mol Genet 20, 3119-28.
(2011) Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia J Biol Chem 286, 14237-45.
(2011) mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression Kidney Int 79, 502-11.
(2011) Rapidly progressive hepatic alveolar echinococcosis in an ABO-incompatible renal transplant recipient Transpl Infect Dis 13, 278-84.
(2011) mTOR inhibitors and autosomal dominant polycystic kidney disease (authors reply) N Engl J Med 364, 287-288.
(2010) Inversin relays Frizzled-8 signals to promote proximal pronephros development Proc Natl Acad Sci U S A 107, 20388-93.
(2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1 Nat Cell Biol 12, 1115-22.
(2010) Everolimus in patients with autosomal dominant polycystic kidney disease N Engl J Med 363, 830-40.
(2010) Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit Curr Biol 20, 1269-76.
(2010) Long-term outcome of ABO-incompatible living donor kidney transplantation based on antigen-specific desensitization. An observational comparative analysis Nephrol Dial Transplant 25, 3778-86.
(2010) Differential role of Rab proteins in ciliary trafficking: Rab23 regulates smoothened levels J Cell Sci 123, 1460-7.
(2010) A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis Hum Mol Genet 19, 2347-59.
(2010) Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice J Clin Invest 120, 1084-96.
(2010) Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel Biochem Biophys Res Commun 391, 1721-5.
(2010) Wnt signaling and rejuvenation of the adult kidney Nephrol Dial Transplant 25, 34-6.
(2010) PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation Hum Mol Genet 19, 16-24.
(2009) Regulation of ciliary polarity by the APC/C Proc Natl Acad Sci U S A 106, 17799-804.
(2009) Leflunomide therapy for polyomavirus-induced allograft nephropathy: efficient BK virus elimination without increased risk of rejection Transplant Proc 41, 2533-8.
(2009) The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9 Biochem Biophys Res Commun 387, 212-7.
(2009) Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development Proc Natl Acad Sci U S A 106, 8579-84.
(2009) A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum Exp Cell Res 315, 1157-70.
(2009) Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome J Am Soc Nephrol 20, 798-806.
(2009) [Disseminated histoplasmosis with involvement of mediastinum and skin in an immunocompetent patient] Dtsch Med Wochenschr 134, 589-93.
(2009) Combination of immunosuppressive drugs leaves specific "fingerprint" on gene expression in vitro Immunopharmacol Immunotoxicol 31, 283-92.
(2009) TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum EMBO J 28, 490-9.
(2009) Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli J Biol Chem 284, 2923-33.
(2009) ABO-incompatible kidney transplantation with antigen-specific immunoadsorption and rituximab - insights and uncertainties Contrib Nephrol 162, 47-60.
(2009) Increased expression of secreted frizzled-related protein 4 in polycystic kidneys J Am Soc Nephrol 20, 48-56.
(2008) Genetic and physical interaction between the NPHP5 and NPHP6 gene products Hum Mol Genet 17, 3655-62.
(2008) TRPP2 and TRPV4 form a polymodal sensory channel complex J Cell Biol 182, 437-47.
(2008) Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity J Biol Chem 283, 23033-8.
(2008) Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin J Cell Sci 121, 1887-98.
(2008) Flow modulates centriole movements in tubular epithelial cells Pflugers Arch 456, 1025-35.
(2008) The subcellular localization of TRPP2 modulates its function J Am Soc Nephrol 19, 1342-51.
(2008) Pathogenesis of nephronophthisis and medullary cystic kidney disease. Molecular and genetic basis of renal disease (edited by D. B. Mount and M. R. Pollak) Philadelphia: Saunders Elsevier.
(2007) Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2 Biochem Biophys Res Commun 364, 861-6.
(2007) Preemptive postoperative antigen-specific immunoadsorption in ABO-incompatible kidney transplantation: necessary or not? Transplantation 84, S40-3.
(2007) Sensitive cilia set up the kidney Nat Med 13, 1409-11.
(2007) Quiz page December 2007: diarrhea and anuria in a recipient of an en bloc infant kidney transplant Am J Kidney Dis 50, A41-3.
(2007) Nephrogenic systemic fibrosis following exposure to gadolinium-containing contrast agent Clin Nephrol 68, 249-52.
(2007) OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum J Biol Chem 282, 36561-70.
(2007) cDNA microarray analysis of adaptive changes after renal ablation in a sclerosis-resistant mouse strain Kidney Blood Press Res 30, 377-87.
(2007) Successful liver transplantation in a kidney and pancreas allograft recipient with fulminant herpes simplex virus type 2 hepatitis Nephrol Dial Transplant 22, 3334-7.
(2007) Quiz page. Renal AA amyloidosis with vascular predominance, secondary to rheumatoid arthritis Am J Kidney Dis 49, A49-50.
(2007) Quiz page. Minimal change glomerulonephritis associated with secondary syphilis Am J Kidney Dis 49, A49-50.
(2007) On-demand strategy as an alternative to conventionally scheduled post-transplant immunoadsorptions after ABO-incompatible kidney transplantation Nephrol Dial Transplant 22, 3048-51.
(2007) Von hippel-lindau: a tumor suppressor links microtubules to ciliogenesis and cancer development Cancer Res 67, 4537-40.
(2007) Wnt signaling in polycystic kidney disease J Am Soc Nephrol 18, 1389-98.
(2007) Prime time for polycystic kidney disease: does one shot of roscovitine bring the cure? Nephrol Dial Transplant 22, 2133-5.
(2007) Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1) Pflugers Arch 453, 819-29.
(2006) Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways Syst Biol (Stevenage) 153, 433-47.
(2006) The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels EMBO J 25, 5659-69.
(2006) The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth J Cell Biol 175, 547-54.
(2006) Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels Proc Natl Acad Sci U S A 103, 17079-86.
(2006) A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9 Biochem Biophys Res Commun 351, 571-6.
(2006) Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis J Comp Neurol 498, 466-75.
(2006) Polycystic kidney disease: cell division without a c(l)ue? Kidney Int 70, 854-64.
(2006) Host cell responses induced by hepatitis C virus binding Hepatology 43, 1326-36.
(2006) Therapeutic approaches in autosomal dominant polycystic kidney disease (ADPKD): is there light at the end of the tunnel? Nephrol Dial Transplant 21, 1752-7.
(2006) The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4 Nat Genet 38, 674-81.
(2006) Remission of polyomavirus-induced graft nephropathy treated with low-dose leflunomide Nephrol Dial Transplant 21, 2039-40.
(2006) ABO-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab: a single center experience Xenotransplantation 13, 108-10.
(2006) Cilium-generated signaling: a cellular GPS? Curr Opin Nephrol Hypertens 15, 245-9.
(2006) The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease Proc Natl Acad Sci U S A 103, 5466-71.
(2006) Gene profiling of polycystic kidneys Nephrol Dial Transplant 21, 1816-24.
(2006) The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals Oncogene 25, 3397-407.
(2006) Cell and molecular biology in medicine: Basic science and clinical relevance in the example of autosomal polycystic kidney diseases. Fortschritte in der Inneren Medizin.
(2005) Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia EMBO J 24, 4415-24.
(2005) Slit or pore? A mutation of the ion channel TRPC6 causes FSGS Nephrol Dial Transplant 20, 1777-9.
(2005) Subcellular localization and trafficking of polycystins Pflugers Arch 451, 286-93.
(2005) NEPH2 is located at the glomerular slit diaphragm, interacts with nephrin and is cleaved from podocytes by metalloproteinases J Am Soc Nephrol 16, 1693-702.
(2005) Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2 Br J Haematol 129, 138-50.
(2005) Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation EMBO J 24, 705-16.
(2004) An inwardly rectifying whole cell current induced by Gq-coupled receptors Biochem Biophys Res Commun 322, 177-85.
(2004) Thrombotic microangiopathy associated with unusual viral sequences in HIV-1-positive patients Nephrol Dial Transplant 19, 1129-35.
(2003) Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains Hum Mol Genet 12, 3397-405.
(2003) [Pathogenetic aspectics of nephrotic syndrome] Internist (Berl) 44, 1075-82.
(2003) Expression profiling on chronically rejected transplant kidneys Transplantation 76, 539-47.
(2003) Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling Mol Cell Biol 23, 4917-28.
(2003) Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1 J Am Soc Nephrol 14, 918-26.
(2003) The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1 J Biol Chem 278, 13417-21.
(2003) NEPH1 defines a novel family of podocin interacting proteins FASEB J 17, 115-7.
(2002) [Pathogenesis of cystic kidney diseases] Verh Dtsch Ges Pathol 86, 138-44.
(2002) Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha J Biol Chem 277, 32954-62.
(2002) The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells J Clin Invest 109, 481-9.
(2001) Interaction with podocin facilitates nephrin signaling J Biol Chem 276, 41543-6.
(2001) Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2 Proc Natl Acad Sci U S A 98, 9784-9.
(2001) Control of the cystic fibrosis transmembrane conductance regulator by alphaG(i) and RGS proteins Biochem Biophys Res Commun 281, 917-23.
(2001) The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel J Biol Chem 276, 4093-101.
(2000) Quantitative trait loci modulate renal cystic disease severity in the mouse bpk model J Am Soc Nephrol 11, 1253-60.
(2000) 14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity J Biol Chem 275, 28167-72.
(1999) Interaction between RGS7 and polycystin Proc Natl Acad Sci U S A 96, 6371-6.
(1999) Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2 Mol Cell Biol 19, 3423-34.
(1999) Modulation of renal tubular cell function by RGS3 Am J Physiol 276, F535-43.
(1999) Specific association of the gene product of PKD2 with the TRPC1 channel Proc Natl Acad Sci U S A 96, 3934-9.
(1999) The polycystic kidney disease 1 gene product modulates Wnt signaling J Biol Chem 274, 4947-53.
(1998) Wnt signaling and transcriptional control of Siamois in Xenopus embryos Proc Natl Acad Sci U S A 95, 5626-31.
(1997) Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2 Proc Natl Acad Sci U S A 94, 6965-70.
(1997) T cell adhesion to P-selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates J Immunol 158, 1061-7.
(1996) Suppression of cell-mediated and humoral immune responses by an interleukin-2-immunoglobulin fusion protein in mice J Clin Invest 97, 1204-10.
(1995) Protein loss and genetic polymorphism of apolipoprotein(a) modulate serum lipoprotein(a) in CAPD patients Nephrol Dial Transplant 10, 75-81.
(1994) A sialyl-Le(x)-negative melanoma cell line binds to E-selectin but not to P-selectin Cancer Res 54, 1109-12.
(1993) T cells bind to the endothelial adhesion molecule GMP-140 (P-selectin) Transplantation 56, 1213-7.
(1992) Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease Dig Dis Sci 37, 818-26.
(1991) Promotion of B cell stimulation in graft recipients through a mechanism distinct from interleukin-6 gene superinduction Transplantation 51, 1312-5.
(1991) Effects of diltiazem upon metabolism and immunosuppressive action of cyclosporine in kidney graft recipients Transplantation 52, 280-4.
(1991) CD62/P-selectin recognition of myeloid and tumor cell sulfatides Cell 67, 35-44.
(1991) The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family J Immunol 147, 3165-9.
(1990) Transcriptional modulation of human IL-6 gene expression by verapamil J Immunol 144, 4242-8.
(1990) Slow accumulation of cyclosporin metabolites as measured by specific and nonspecific cyclosporin RIA Int J Clin Pharmacol Ther Toxicol 28, 167-75.
(1990) A kinetic analysis of the effects of interleukin-2 diphtheria toxin fusion protein upon activated T cells Transplantation 49, 198-201.
(1990) Evidence that glucocorticosteroids block expression of the human interleukin-6 gene by accessory cells Transplantation 49, 183-5.
(1990) Possible association of the immunosuppressive and B cell lymphoma-promoting properties of cyclosporine Transplantation 49, 191-4.
(1990) Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells Science 250, 1132-5.
(1989) Verapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells Transplant Proc 21, 85-7.
(1989) Saturable first-pass kinetics of propranolol J Clin Pharmacol 29, 240-5.
(1989) Multivariate analysis of aminoglycoside levels in hemodialysis patients Chemotherapy 35, 1-6.
(1989) Cyclosporin drug monitoring: comparison of four immunoassays and HPLC Klin Wochenschr 67, 438-41.
(1989) Similar effects of cyclosporine and verapamil on lymphokine, interleukin 2 receptor, and proto-oncogene expression Transplantation 47, 331-4.
(1989) Sequential effects of interleukin 2-diphtheria toxin fusion protein on T-cell activation Proc Natl Acad Sci U S A 86, 9485-8.
(1989) Factors influencing the response to hepatitis B vaccination of hemodialysis patients Nephron 51, 474-7.
(1988) [Beta 2 microglobulin. 2: Dialysis-associated amyloidosis] Fortschr Med 106, 334-7.
(1988) [Beta 2 microglobulin. 1: Physiologic significance, behavior in kidney diseases and chronic hemodialysis] Fortschr Med 106, 331-3.
(1988) Cyclosporin metabolites and central-nervous-system toxicity Lancet 1, 1223.
(1988) Elevated tumor markers in hemodialysis patients Am J Nephrol 8, 187-9.
(1988) The relevance of tissue polypeptide antigen (TPA) in patients with end-stage renal failure. Nieren- und Hochdruckkrankheiten 17, 211-214.
(1988) Cyclosporine blood levels in diltiazem-treated kidney graft recipients. Clin Transplantation 2, 21-25.
(1987) [Effect of diltiazem on blood cyclosporin levels] Klin Wochenschr 65, 1101-3.
(1987) Initial pharmacokinetics and long-term dosage of cyclosporine. Nieren- und Hochdruckkrankheiten 16, 294-296.