Playing in Traffic: Novel Signaling and Trafficking Mechanisms in Epithelial Cells
(2010) Inversin relays Frizzled-8 signals to promote proximal pronephros development Proc Natl Acad Sci U S A 107, 20388-93.
(2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1 Nat Cell Biol 12, 1115-22.
(2010) Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease N Engl J Med.
(2010) Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit Curr Biol 20, 1269-76.
(2010) Differential role of Rab proteins in ciliary trafficking: Rab23 regulates smoothened levels J Cell Sci 123, 1460-7.
(2010) A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis Hum Mol Genet 19, 2347-59.
(2010) Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice J Clin Invest 120, 1084-96.
(2010) Transcription control of early B cell differentiation Curr Opin Immunol 22, 161-7.
(2010) SnAvi--a new tandem tag for high-affinity protein-complex purification Nucleic Acids Res 38, e91.
(2010) Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel Biochem Biophys Res Commun 391, 1721-5.
(2010) Wnt signaling and rejuvenation of the adult kidney Nephrol Dial Transplant 25, 34-6.
(2010) PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation Hum Mol Genet 19, 16-24.
(2009) Immunofluorescence staining of ciliated respiratory epithelial cells Methods Cell Biol 91, 123-33.
(2009) Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects Am J Hum Genet 85, 883-9.
(2009) Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression Genes Dev 23, 2625-38.
(2009) Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus Genesis 47, 775-81.
(2009) Regulation of ciliary polarity by the APC/C Proc Natl Acad Sci U S A 106, 17799-804.
(2009) The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9 Biochem Biophys Res Commun 387, 212-7.
(2009) Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout Proc Natl Acad Sci U S A 106, 10338-42.
(2009) Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development Proc Natl Acad Sci U S A 106, 8579-84.
(2009) A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum Exp Cell Res 315, 1157-70.
(2009) Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome J Am Soc Nephrol 20, 798-806.
(2009) Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth J Biol Chem 284, 16482-91.
(2009) Combination of immunosuppressive drugs leaves specific "fingerprint" on gene expression in vitro Immunopharmacol Immunotoxicol 31, 283-92.
(2009) TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum Embo J 28, 490-9.
(2009) Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli J Biol Chem 284, 2923-33.
(2009) Increased expression of secreted frizzled-related protein 4 in polycystic kidneys J Am Soc Nephrol 20, 48-56.
(2008) Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins Nature 456, 611-6.
(2008) Refining the phenotype of alpha-1a Tubulin (TUBA1A) mutation in patients with classical lissencephaly Clin Genet 74, 425-33.
(2008) DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm Am J Hum Genet 83, 547-58.
(2008) Genetic and physical interaction between the NPHP5 and NPHP6 gene products Hum Mol Genet 17, 3655-62.
(2008) TRPP2 and TRPV4 form a polymodal sensory channel complex J Cell Biol 182, 437-47.
(2008) Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity J Biol Chem 283, 23033-8.
(2008) Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin J Cell Sci 121, 1887-98.
(2008) Flow modulates centriole movements in tubular epithelial cells Pflugers Arch 456, 1025-35.
(2008) The subcellular localization of TRPP2 modulates its function J Am Soc Nephrol 19, 1342-51.
(2008) L: -2-Hydroxyglutaric aciduria: Identification of ten novel mutations in the L2HGDH gene J Inherit Metab Dis.
(2008) Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin Mol Cell Biol 28, 3526-37.
(2008) Multitasking of interferon regulatory factor-4 in early B cells Immunity 28, 295-7.
(2008) An optimized split-ubiquitin cDNA-library screening system to identify novel interactors of the human Frizzled 1 receptor Nucleic Acids Res 36, e37.